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AcneFacts is a website that provides facts and resources to acne problems and tips for clear skin. It is solely for educational purpose and not meant to substitute personal medical advice. |
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How Does Acne DevelopAcne is formed by complex interplay between hormones, excessive sebum production, genetics, and blockage of pore opening, bacteria and the body’s immune response Acne begins at the pilo-sebaceous unit (i.e. the oil-producing gland and associated hair follicle). Around puberty, our oil grand grow in size and start to produce more sebum and is influence by the increasing amount of androgens (i.e. male sex hormones) in the body. Both males and females have androgens, thought the males have a higher levels of it. While the enlarge oil-producing glands increase oil production, the increased and abnormal growth of your cells lining at the opening of the pilo-sebaceous unit results in clogging of the opening, causing retention of the sebum and dead skin cells. This results in the formation of whiteheads and blackheads - the early non-inflamed lesions of acne. The retained mixture of oil and cells allows bacteria that normally live on the skin to grow in the plugged follicles. These bacteria produce chemicals and enzymes and attract white blood cells that cause inflammation. When the wall of the plugged follicle breaks down, it spills everything into your nearby skin--sebum, shed skin cells, and bacteria--leading to lesions or pimples. While the inflammation helps clear the bacteria from the skin, it also destroys tissue around the pilo-sebaceous glands. And this may result to permanent scarring during the healing process.
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